The Ultimate Guide to Tianeptine Sodium 


Depression is one of the most debilitating chronic illnesses which affects around 350 million people worldwide. To come out from this illness people take a lot of treatment like therapy, yoga, and antibiotics. Currently, tianeptine sodium is an effective antidepressant that easily reduces the impact of depression on a body. 

How does tianeptine sodium work?

Tianeptine has useful impacts in various behavioral models identified with depression, tension, and different pressure related disorders. Tianeptine has been appeared to balance glutamatergic transmission, and its consequences for neuroplasticity have been widely examined in the hippocampus and amygdala. For instance, tianeptine reestablishes pressure incited decrease of dendritic arborization in hippocampal neurons. Additionally, tianeptine switches pressure incited hindrance of long haul potentiation at excitatory neurotransmitters in the hippocampus and prefrontal cortex. Although tianeptine has been appeared to tweak N-methyl-D-aspartate (NMDA) andα-amino-3-hydroxy-5-methyl-4-isoxazole propionic corrosive (AMPA) receptor function, a few reports have demonstrated that tianeptine has no quantifiable partiality for these receptors2 and doesn’t tie considerably to monoamine synapse receptors, kainate receptors or monoamine transporters.

Importance of tianeptine sodium:

Tianeptine is an antidepressant with a novel neurochemical profile. It expands serotonin (5-hydroxytryptamine; 5-HT) take-up in the brain (interestingly with antidepressant specialists) and decreases pressure incited decay of neuronal dendrites. Like the specific serotonin reuptake inhibitors (SSRIs) and interestingly with most tricyclic stimulant specialists, tianeptine doesn’t seem, by all accounts, to be related to antagonistic subjective, cognitive, sleep, cardiovascular or bodyweight impacts and has a low propensity for abuse. Tianeptine has a similarly positive pharmacokinetic profile. 


The dosage ought to be decreased in old patients and those with extreme renal failure, however, change isn’t important in patients with alcoholism or hepatic hindrance, or those experiencing hemodialysis. Ends: The stimulant viability and ideal fairness and pharmacokinetic profiles of tianeptine in patients with melancholy, incorporating those with related uneasiness, have been demonstrated; the information show that it might have extra potential in explicit subgroups of discouraged patients, for example, the old and those with incessant alcohol addiction. Tianeptine sodium buy from an online platform and gets an accurate dosage. 

Features of Tianeptine Sodium:

Tianeptine is an antidepressant agent with a remarkable feature. 

Although it has basic similitudes to tricyclic antidepressants (TCAs), dissimilar to tricyclic operators or particular serotonin-reuptake inhibitors (SSRIs), tianeptine upgrades 5-HT reuptake, prompting diminished accessibility of the transmitter in the synaptic separated. 

Tianeptine has auxiliary similitudes to TCAs, however not at all like TCAs or SSRIs, tianeptine improves 5-HT reuptake. 

Paroxetine is an intense inhibitor of 5-HT reuptake and a powerless inhibitor of NE reuptake. 

So the pharmacological methods of activity of these two medications are extraordinary and a second compound from an alternate pharmacological family is valuable in patients with single medication treatment-resistant depression. 

Final Say:

We hope now you understand the role of tianeptine sodium in depression. If you are suffering from depression and looking for an effective treatment then you should go to tianeptine sodium buy. Before buying it, just consult with your doctor and get a better opinion from him. 


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